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  » Men's health  »  Benefits and Risks of Testosterone Therapy

There have been no large, long-term studies to tell us the benefits and risks of using testosterone replacement therapy. For the studies that have been done, researchers are not always in agreement about the benefits and risks of trT. More research needs to be done. At this point, here’s what studies are reporting.


Testosterone replacement therapy may have these benefits:

  • Improved libido
  • More energy and improved sense of well-being
  • Increase in bone and muscle mass
  • Improved body composition
  • Better mood
  • Rise in hemoglobin levels to the normal range. Hemoglobin helps red blood cells carry oxygen from your lungs to all parts of your body.


Testosterone replacement therapy might have these risks:

  • Higher chance of prostate cancer
  • Rise in hemoglobin levels above the normal range
  • Problems passing urine, also called voiding symptoms. This includes poor urine flow, feeling like you can’t empty your bladder, or hesitancy before urinating.
  • Liver damage from oral preparations of testosterone
  • Sleep apnea (stopping breathing during sleep)
  • Breast tenderness and swelling
  • Testicles get smaller
  • Fertility problems while using trT
  • Skin reaction from patches or gel
  • Pain, soreness, or bruising from injection
  • Fluid retention
  • Acne
  • Oily skin
  • Increased body hair