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   Skin Whitening Product List
Get white soon and permanently
Now, science has made it easier for you to reveal that beauty within.
Don"t" miss this chance!

Important scarce mesotherapy anti-aging and skin whitening products

FOR A FULL COURSE OF TREATMENT:

(3 boxes): Vitacicol USA. 1 box contains 10 vials which also contains whitening agent called thiourea which is very effective for skin whitening

$ 308.75 for 1box
$ 850.00 for 3 boxes

(3 boxes): Tationil Glutathione/Biotad Glutathione/ from Roche which can help you to get faster result. this product also has 10 vials per box.

Biotad Glutathione
1 to 9 boxes $248.75 per box,
10 to 50 boxes $241.25 per box,
more than 50 boxes $230.00 per box

Tationil Glutathione
$ 298.75 for 1 to 9 boxes,
$ 258.75 for 10 to 20 boxes,
$ 231.25 for 21 to 40 boxes

vit c + collagen + 65% DNA complex: 1 box
Price per box-$ 742.5 for 1 box

You may definitely start with one box of each but keep in mind that the total treatment for permanent results will be 3 boxes. There is an added financial incentive to purchase three boxes at one time as well.

QUOTE: (1 box of each)

1. vitacicol usa 1 box
2. tationil glutathion 1 box
3. vit c + collagen + 65% dna complex 1 box

PRICE- Inclusive of courier shipping: $ 1278.25 only

For the full course of:

3 boxes of vitacicol USA
3 boxes of tationil glutathion
1 box of vit c + collagen + 65% DNA complex

PRICE - Inclusive of courier shipping:
$ 2217.50 only

Detailed prescribing information of each of the above products

Common topical treatments
Even with all the products manufactured, they all still use several basic ingredients, all of which work to a degree. As you"ll read further down, some have side effects, and some work better for some skin types that others. Your best source of information however, would be a dermatologist, who can examine your skin and help you select the best product for you. I"ve collected quite a few sites that explain the different products; pros and cons. Please check each link for complete information. You"ll notice that I gathered my information, primarily from sites that do NOT sell products!“When it comes to selecting treatment for these areas, one factor to consider is the depth of the discolored pigment. Most of the time discoloration is superficial. In a few cases, the discoloration lies deep in the dermis. If the pigment is in the epidermis, it can be helped with skin-lightening products. If the pigment is deeper, laser treatments are a consideration. For topical treatments, according to an article in The American Journal of Clinical Dermatology (September-October 2000, pages 261–268),"[T]opical hydroquinone 2 to 4% alone or in combination with tretinoin 0.05 to 0.1% is an established treatment. Topical azelaic acid 15 to 20% can be as efficacious as hydroquinone…. Tretinoin is especially useful in treating hyperpigmentation of photoaged skin. Kojic acid, alone or in combination with glycolic acid or hydroquinone, has shown good results, due to its inhibitory action on tyrosinase. Chemical peels are [also] useful to treat melasma." http://www.cosmeticscop.com/learn/article.asp?PAGETYPE=ART&REFER=SKIN&ID=25

“Among skin-lightening agents, hydroquinone (HQ) is one of the most widely prescribed agents in the world. However, with reports of potential mutagenicity and epidemics of ochronosis in African nations, there has been increasing impetus to find alternative herbal and pharmaceutical depigmenting agents. A review of the literature reveals that numerous other depigmenting or skin-lightening agents are in use or in investigational stages. Some of these, such as kojic and azelaic acid, are well known to most dermatologists. Others more recently have been discovered and reported in the literature.” “The 2% HQ is readily available over-the-counter in various cosmetic preparations. However, for better efficacy, it often is compounded into various mixtures for treatment of hyperpigmentation. The original Kligman formula involves compounding 5% HQ with 0.1% retinoic acid and 0.1% dexamethasone in a hydrophilic ointment base. Concentrations as high as 10% can be compounded extemporaneously for refractory cases. Evidence of improvement with HQ (monotherapy) usually is observed at 4-6 weeks, with improvement appearing to plateau at about 4 months. Despite its remarkable overall safety, the physician ought to bear in mind the potential adverse effects. Contact dermatitis occurs in a small number of patients and responds promptly to topical steroids. An uncommon, yet important, adverse effect of HQ is exogenous ochronosis. This disorder is characterized by progressive darkening of the area to which the cream containing HQ is applied. Histologically, degeneration of collagen and elastic fibers occurs. This degeneration is followed by the appearance of characteristic ochronotic deposits consisting of crescent-shaped, ochre-colored fibers in the dermis.” http://www.emedicine.com/derm/topic528.htm

“Skin-whitening products work in various ways. Some contain acids that remove old skin to reveal newer, lighter skin underneath. Others inhibit melanin, like those with mulberry extract, licorice extract, kojic acid, arbutin and hydroquinone, an ingredient in prescription creams for blemishes as well as in photo processing materials. Some of the most effective agents are also risky — and are often the least expensive, like mercury-based ingredients or hydroquinone, which in Thailand sells for about $20 per kilogram (2.2 pounds), compared with highly concentrated licorice extract, which sells for about $20,000 per kilogram. Hydroquinone has been shown to cause leukemia in mice and other animals. The European Union banned it from cosmetics in 2001, but it shows up in bootleg creams in the developing world. It is sold in the United States as an over-the-counter drug, but with a concentration of hydroquinone not exceeding 2 percent.” http://www.nytimes.com/2006/05/14/
world/asia/14thailand.html?ex=1305259200&en=58475681dbd045a9&ei=5088&partner=rssnyt&emc=rss

Mainly the Skin Whitening Ingredients works in two ways to give you a whiter skin: 1. By absorbing the UV rays, thus preventing the sun from darkening your skin. 2. By reducing the production of melanin, the skin pigment found in your skin which is responsible for skin darkening. Here are some of the ingredients you may find in your skin whitening products:

Kojic Acid: It is used to lighten the skin in Japan. It is a tyrosinase inhibitor. That would explain how it reduces the production of skin pigment, melanin.
Licorice Extract: This absorbs the UVA and UVB rays. It also is a depigmenting agent and inhibits the production of melanin. Aloe Vera: Aloe Vera appears to absorb UV light. That would account for its mild skin lightening abilities.
Octyl-p-methoxycinnamate: This is a sunscreen. It absorbs UV light very well, preventing the UV rays from darkening your skin.
Octyl salicylate: This is a salt of the saliculic acid that is found in wintergreen leaves. It is a sunscreen, found in sun tan lotions.
Oxybenzone: This is a sunscreen chemical that absorbs UVA rays. http://www.ultimate-cosmetics.com/skin-whitening.htm

“By the National Poison Centre Q: Hydroquinone creams were highlighted recently as adverselyaffecting the skin. Can you explain the use of these products and their effects? A: The recent statement by the Minister of Health against beauticians prescribing skin bleaching products containing more than two per cent hydroquinone follows the world-wide concerns about the use of such products (NST, Feb 2). The move to create awareness about the adverse effects caused by these products was needed considering that the demand for them has increased so much that they are now illegally manufactured here to meet demand.Although they serve a cosmetic function in lightening skin colour, it must be known that these products are drugs and have potentialtoxicity if used without advice from doctors. Originally, a number of topical agents have been used in skin-bleaching preparations.
These included hydroquinone, the monobenzyl and monomethyl esters of hydroquinone, ammoniated mercury, ascorbic acid and peroxides. Unfortunately, most of these agents have limited clinical use because of their effects and resultant complications.
For example, mercury compounds have been used with varying success to lighten skin pigment. The mercury ions are thought to inhibit the
synthesis of melanin, a black pigment responsible for darkening the skin.” “Darker lesions repigment faster than lighter lesions. Because the ability of the sun to darken lesions is greater than that of hydroquinone to
lighten them, strict avoidance of sunlight is important. The effectiveness of hydroquinone varies among patients.
In a US study, hydroquinone two per cent and five per cent creams were applied on the hyperpigmented skin of 56 patients with
12 per cent of the patients being black. Hydroquinone cream was applied twice daily and the treatment was continued for three months. Hydroquinone was effective as a
depigmenting agent in 44 of the cases. The use of hydroquinone five per cent cream was accompanied by adverse effects, mainly irritation. However, at the lower concentration (two per cent cream), the drug appeared to be equally effective therapeutically with fewer irritant reactions.
From the result, it seems that hydroquinone is best on lighter skin and on lighter lesions.” http://www.prn2.usm.my/mainsite/bulletin/nst/1998/nst12.html

“Depigmentation is a treatment in which a person may choose to remove the pigmentation from the unaffected skin areas to better match the affected areas. This is used in cases where vitiligo is extensive. The person uses a cream containing monobenzyl ether of hydroquinone to remove remaining pigment. This process takes a long time to complete, sometimes a year or more. Removal of pigment is permanent” http://www.mediresource.com/sdm/sdm/english/disease_detail.asp?disease_id=302

Hydroquinone is a common skin bleach, intended to fade age spots and small skin discolorations. Some products that contain hydroquinone Eldopaque, Eldopaque Forte, Eldoquin-Forte Sunbleaching, Esoterica Facial, Esoterica Regular,
Esoterica Sunscreen, Melquin HP, NeoStrata AHA Gel for Age Spots and Skin Lightening, Nuquin HP, Solaquin, Solarquin Forte “What drug(s) may interact with hydroquinone?
benzoyl peroxide Check with your prescriber if you are using other medications which are applied to the skin. Non-medicated cosmetics, sunscreens, and moisturizing lotions may be worn over the hydroquinone preparation. However, wait several minutes after application of hydroquinone before applying them.” Please read the entire site for further information. http://www.drugdigest.org/DD/DVH/Uses/0,3915,6150%7CNeoStrata+AHA+Gel+for+Age+Spots+and+Skin+Lightening,00.html

“Over-the-counter skin-lightening products often contain 2% hydroquinone, while 4% concentrations are available only from a physician.
Hydroquinone is a strong inhibitor of melanin production (source: Journal of Dermatological Science, August, 2001, Supplemental pages S68–S75), meaning that it lightens skin color.
Hydroquinone does not bleach the skin (calling it a bleaching agent is a misnomer); it only disrupts the synthesis of melanin hyperpigmentation. In the medical literature Hydroquinone is considered the primary topical ingredient for inhibiting melanin production.
Using it in combination with the other options listed can make a difference in skin discolorations (Sources: Journal of Cosmetic Science,
May-June 1998, pages 208–290; Dermatological Surgery, May 1996, pages 443–447). Some concerns about hydroquinone"s safety on skin have been expressed, but the research indicates reactions are minor or a result of using extremely high concentrations (Source: Critical Reviews in Toxicology, May 1999, pages 283–330).” “Hydroquinone can be an unstable ingredient in cosmetic formulations. When exposed to air or sunlight it can turn a strange shade of brown. It is essential, when you are considering a hydroquinone product, to make sure it is packaged in a non-transparent container that doesn"t let light in and minimizes air exposure. Hydroquinone products packaged in jars are not recommended, because they become ineffective shortly after opening.” http://www.cosmeticscop.com/learn/article.asp?PAGETYPE=ART&REFER=SKIN&ID=25

Tretinoin
---------

“Results can also take far longer with tretinoin than with other treatments, requiring at least six months or so before improvement is seen.
Because of this, tretinoin is generally not recommended as the only option for skin discoloration but it can be used in combination with other effective topicals (source: eMedicine Journal, www.emedicine.com, November 15, 2001, Volume 2, Number 11). Even though tretinoin can be disappointing for skin lightening, that should in no way diminish the role it plays in the improvement in skin"s cell production, collagen production, elasticity, texture, and dermal thickness. Tretinoin, combined with more effective skin-lightening treatments, is a powerful alliance in the battle against sun-damaged and aged skin.” http://www.cosmeticscop.com/learn/article.asp?PAGETYPE=ART&REFER=SKIN&ID=25

Alpha Hydroxy Acids
--------------------

”In and of themselves, alpha hydroxy acid products in concentrations of 4% to 10% are not effective for inhibiting melanin production and won"t lighten skin discolorations. However, there is evidence that in combination with other treatments such as kojic acid, hydroquinone, azelaic acid, and laser resurfacing they can be very effective for improving the overall appearance of sun-damaged skin and possibly helping the other ingredients penetrate the skin better. Much like laser treatments, alpha hydroxy acid peels (using 50% concentrations) have impressive results for removing skin discolorations (Source: Dermatological Surgery, June 1999, pages 450–454). Only a physician should perform these types of facial peels.” http://www.cosmeticscop.com/learn/article.asp?PAGETYPE=ART&REFER=SKIN&ID=25

Kojic Acid
----------

”Kojic acid is a by-product in the fermentation process of malting rice for use in the manufacturing of sake, the Japanese rice wine. There is convincing research, both in vitro (in a test tube) and in vivo (on a live subject), showing kojic acid to be effective for inhibiting melanin production (Source: Archives of Pharmacal Research, August 2001, pages 307–311). Glycolic or kojic acid, or glycolic acid with hydroquinone, are highly effective in reducing the pigment in melasma patients” http://www.cosmeticscop.com/learn/article.asp?PAGETYPE=ART&REFER=SKIN&ID=25

Magnesium ascorbyl phosphate
-----------------------------

Magnesium-L-ascorbyl-2-phosphate (MAP) is a stable derivative of ascorbic acid. When used as a 10% cream, MAP was shown to suppress melanin formation. A significant lightening effect was seen clinically in 19 of 34 patients with melasma and solar lentigos. Furthermore, MAP has been shown to have a protective effect against skin damage induced by UV-B irradiation. The latter protective effect is because of the conversion of MAP to AS.” http://www.emedicine.com/derm/topic528.htm

“Dermatologists claim that there is no such thing as a fairness cream, certainly not without using skin-bleaching agents such as hydroquinone, steroids, mercury salts, and a number of other ingredients including bismuth subnitrate, hydrogen peroxide, magnesium peroxide and zinc peroxide.” All of these ingredients, says Prof ABM Faroque, Chair, Department of Pharmaceutical Technology, University of Dhaka, can cause, among more serious health hazards, nephrotoxicity, mercury toxicity and serious allergic reactions. Nephrotoxicity refers to irritation to nephrons in the kidney, causing kidney damage. Mercury toxicity includes effects like metallic taste, increased thirst, abdominal pain, bloody diarrhoea, nephritis, decreased flow of urine, colitis or constipation, tremors, anaemia, and skin problems. Mercury has adverse effects on the developing brain of a foetus. Fairness cream market leader in Bangladesh, Fair and Lovely, however, claims that it does not use any skin-bleaching agents and neither does its formulation include any harmful ingredients like hydroquinone, steroids or mercury. According to scientists at Unilever, Fair and Lovely "lightens skin safely and reversibly through a synergistic and patented combination of" Vitamin B3 (niacinamide) and a mixture of US FDA- and EU-approved UV-A and UV-B sunscreens. Ayurvedic Fair and Lovely also contains natural skin-lightening agents such as Kumkumadi Tailum. Unilever claims that niacinamide topically applied is effective in reducing hyperpigmentation and lightening skin colour and that it is also beneficial in terms of anti-ageing, overall skin texture, etc. http://www.thedailystar.net/magazine/2006/05/02/cover.htm

“Dermal pigmentation disorders, such as melasma, arise from increased melanin in the epidermis and increased free melanin and melanophages. The pigmentation occurs deeper in the skin, and has a less distinct border. The pigmentation is brown, but the color may be mixed with gray or blue. In general, dermal pigmentation disorders are difficult to treat. "Bleaching creams are the most frequently used therapies, but the efficacy is less than ideal," Dr. Zhou says. "Better therapies are needed." http://mediwire.skyscape.com/main/Default.aspx?P=Content&ArticleID=188726

“Even a little bit of sun worshipping can cause age spots later in life. Sunlight contains ultraviolet rays that cause suntans and burns. As time goes by, tanning causes more pigment than normal to be deposited in the skin. This leads eventually to flat, brown skin lesions known as age spots. They"re also known as liver spots or sun spots. Symptom Relief Age spots are harmless. They"re benign and they do not go on to become any type of skin cancer or premalignant skin lesion," Dr. Clark says. But because some skin cancers such as melanoma can look like age spots, you should ask your doctor to examine your skin during your annual checkup. Here are a couple of ways to deal with these telltale signs of excessive sun exposure. Bleach it out. If your age spots aren"t too dark or large, over-the-counter skin-bleaching creams containing hydroquinone could help them fade away, says Marc Bauder, M.D., a family practice physician in Sun City West, Arizona. Be sure to follow the manufacturer"s directions carefully when applying the cream to your skin. Don"t overexpose yourself. The best way to treat and prevent age spots is to cut the time you spend in the sun. Once you have these spots, sunlight can make them appear darker and more prominent, Dr. Bauder says. To prevent that, always wear a sun block that has a sun protection factor (SPF) of at least 15 on exposed skin. In addition, try to wear a long-sleeved shirt and a broad-brimmed hat whenever you"re outdoors.” Ask about a peel. When someone has dozens of age spots, doctors suggest a trichloroacetic acid chemical peel (TCA), says Dr. Clark. The peel, which is applied in a doctor"s office, removes the top layer of skin where the spot is located.” http://www.mothernature.com/Library/Bookshelf/Books/16/3.cfm

“To help keep hands looking young, use a specially formulated hand cream with sun block at least once a day. To treat age or “liver” spots, dermatologists can use Retin A to help lighten small spots over time. Hydroquinone, a bleaching cream, often is used to lighten the spots, but some European scientists have questioned the drug"s safety in recent years. Liquid nitrogen, laser treatment, and chemical peels are some other options. The best way to avoid age spots is to stay out of the sun. “Sun exposure is one of the most common environmental
sources for aging the skin,” Ali says. “It increases the risk for skin cancer and photo-aging.” http://www.uthouston.edu/hleader/archive/Dermatology/2005/agingskin-1018.html

“...about half of all Thai dermatologists prescribed creams with hydroquinone. He stopped prescribing it a decade ago when he noticed patients with redness and itching and with more serious side effects like ochronosis, the appearance of very dark patches of skin that are difficult to remove. Some patients also develop leukoderma, where the skin loses the ability to produce pigment, resulting in patches of
pink like those on Ms. Panya"s face and neck. When she first began using the cream, which was packaged under the name 3 Days and cost the equivalent of $1, she said she was very happy with the results. Her skin started itching, but she tolerated it because her complexion lightened considerably. She got bigger tips at the restaurant,
where she sang folk songs, she said. But when her face became blotchy two months later, her boss told her she could no longer sing at the restaurant because she was unsightly.” http://www.nytimes.com/2006/05/14/world/asia/14thailand.html?pagewanted=2&ei=5088&en=58475681dbd045a9&ex
=1305259200&partner=rssnyt&emc=rss

“In clinics in Arizona, for example, doctors had observed more than 300 patients who had toxic levels of mercury in their urine. I found medical reports of similarly high levels of mercury poisoning among patients in Saudi Arabia, Senegal, West Africa, and in Tanzania in East Africa. Even among newly arrived Bosnian and Albanian refugees in Germany, doctors have found patients with toxic levels of this same type of mercury. One of my first clues to unraveling this mystery turned out to be basic geography: Most of the reported mercury-poisoning cases were found in nations in the lower latitudes. The second clue: In Mexico, as in other countries such as Saudi Arabia and Pakistan, most of the patients with clinical evidence of mercury poisoning were women. Even in the Southwestern Unites States, 96 percent of the more than 300 patients found to have abnormal mercury levels were female. In every case, clinical questioning revealed that the women had used skin-whitening creams -- many for years. In other words, these women had tried so desperately to whiten their skin color that they had poisoned their bodies by applying mercury-based "beauty creams." http://www.boston.com/news/globe/health_science/articles/2003/12/16/whitening_skin_can_be_deadly/ Interesting research http://www.scienceboard.net/community/memberSpotlight.asp?spotid=15

“If you have age spots, you"re at a higher risk of developing skin cancer, so it is important to see your doctor if they change colour or appearance or if you are worried about them. Once your doctor gives you a clean bill of health, discuss the various options for minimising the appearance of age spots. There are several over-the-counter and prescription treatments for age spots, available at your local chemist. Remember, though, that with whichever method you choose, results will vary depending on how severe the spots are, how much time you spend in the sun and how consistently you follow treatment. It"s essential to protect your skin against new age spots and prolong the result of treatment by wearing sunscreen on all exposed areas of the body every day, even in winter.” http://www.ivillage.co.uk/beauty/skincare/aging/qas/0,,547681_183592,00.html

There you go! It appears that retinoids and hydroquinone"s may be the most effective type of cream, but each ahs it"s own drawbacks, as you have read. Remember that in order to work, the creams must be applied as the label states, and used regularly, over several months before seeing results. Remember too that staying out of the sun as much as possible is necessary to prevent further skin damage. When in the sun, use a good sunscreen and a hat! I would suggest discussing this with your dermatologist. From my research, I found that different products work differently
for each person. It could take years before you found the product that works best for your skin. Your doctor can also rule out any skin conditions and perhaps suggest a prescription strength lightener.

Generalised skin whitening agents
Beauty is skin deep but it"s the SKIN that matters most
The SKIN is the largest organ of the body and maintaining its youthful glow, elasticity and tone is a MUST.
As we age, so is our skin that is why it is essential to take more care of it since it is the outer layer of the
body to which people perceives by their senses. To some people, skin is such a big issue because most of the
time it suggests status symbol in the society.
Most people tends to believe that if you have a flawless and light skin it means that you belong to the upper
class or you"re a celebrity, because of that simple reason, people would kill for that light and flawless skin.

Achieving a nice skin is not an easy task and it requires a lot of work, discipline and patience. You"re lucky
enough if you innately possess that celebrity-like skin that anybody would envy, but how about those people who aren"t that lucky as you are? There are a few basics which you need to do in order to take care of your skin. Everybody knows that water is a basic need and believe me it does wonders in your skin and so drinking lots of everyday especially if you sweat a lot is a very good habit. Avoid the sun. Never go outside unprotected, at least use an umbrella and put sunblock whenever you need to go outside. The skin also needs some light from the sun but basically its UV rays that penetrates to the skin only increases melanin production resulting into a darkened skin. Some people nowadays don"t seem to have sufficient sleep due to work and other things they do but according to studies
having sufficient sleep(roughly about 6-8hrs/day) gives more time for your skin you regenerate. Having a healthy skin correlates to a healthy environment. Breathing clean air and living in a smoke-free environment is also a factor for good and healthy skin. People who don"t smoke look more radiant than people who do. What you eat is what you get. Invest in fiber-rich fruits and vegetables and avoid, if possible, fats and high-carb diet. Fiber-rich fruits and veggies does great in your body for it maintains good bowel and cleanses the digestive track, remember, a clean system registers a clear skin. Finally, if you have done all sorts of healthy habits and you seem to feel that it"s not enough nor it does not help your skin dilemma, then its time for science to work for your skin.

Ever wished for that light and flawless skin most celebrities have? Do you know their secret in achieving that porcelain complexion as seen on TV? Not everybody knows about this wonder supplement but it is the secret in achieving such fantastic skin and at the same time improving over all health. It was used in the early years as anti-oxidant, anti-aging and even given(intravenous) to people with HIV/AIDS since this supplement boosts the immune system. Surprisingly, it was discovered that taking it in high dose and in long term evidently lightens the color of the skin, moreover, this is its side-effect alone thus promoting better health. Glutathione is a tripeptide amino-acid that mainly resides in the liver, it is in existence in the body and its supplementation is essential for the body to be able to function fully. Oral administration of this supplement, taking in consideration the proper dosage, surely will lighten your skin and achieve that youthful glow.

Glutathione has a scientific basis in how it works as skin lightener and it is a logical fact. There are even studies made about its skin lightening properties:
http://www.blackwell-synergy.com/links/doi/10.1111/j.1467-2494.2005.00235.x/abs/

Products
  • Vitacicol Whitening U.S.A
  • Mita-C Whitening -Mita-Pharma Japan
  • Vitamin C + Kollagen & 65% DNA Whitening Manufacturer: SCHIMTCH-GmbH & CO. GERMANY AG
  • Tationil Glutathione/Biotad Glutathione, Italy

FAQ
  • Q 1. Which skin whitening product really works?
  • Answer: There are certainly a lot of skin whitening products on the market – even more than I imagined!
  • Q 2. Can I obtain an all over whitish palish complexion ( and I am talking about getting from dark brown to light brown)??
  • Answer: by only using 1 box of this product (contains 4 vials for whitening) is not enough to get a result from dark brown to light brown. Actually the main target for using this product is not only for whitening, we usually recommend this product for skin firming. To smooth out wrinkles and fine lines around the area of eyes, face, chin and body skin, to increase the volume of lips, to
  • Q 3. Do you have clients that have used this particular product and they are happy with it?
  • Answer: Yes, we do. actually this product is quite new in the market; up to this time, none of our customer using this product have ever complaint and some of them even contact us back to tell us the result and they are very satisfied. One of our clients told us that she used the product after deliver her baby and after just finished the whole treatment, she already see the result. her skin become firmer, as well as her breast, and the thing she was most happy with is that her nipple become slightly pinkish colour.
  • Q 4. With one box will I see results (and what results do i expect to see)?
  • Answer: Actually the Vitamin C+Kollagen, SCHIMTCH and the Vitamin C + Kollagen & 65% DNA Whitening, SCHIMTCH are our fastest product to get the result. Usually it is just within 2 weeks (you may notice he effect during the treatment), this is due to the strengh of the collagen whereby it has 375mg of collagen in 1 vial. you may feel your skin become firmer, fine lines in the face diminish, the breast and buttock get firmer and so on; it can also helps to eliminate scars.
  • Q 5. When I start using this product do I stop using any lightening lotion?
  • Answer: You can choose whether to continue using lotion or to stop but to make sure your skin stay fair, you should protect yourself from direct sunlight by using SPF or sunblock.

Synopsis
Glutathione is an ubiquitous compound found in our bodies. Aside from its many ascribed biologic functions,
it has also been implicated in skin lightening. We review in vitro and in vivo studies that show evidence of its involvement
in the melanogenic pathway and shed light on the its anti-melanogenic effect.
Proposed mechanisms of action include: (a) direct inactivation of the enzyme tyrosinase by binding with the copper-containing
active site of the enzyme; (b) mediating the switch mechanism from eumelanin to phaeomelanin production;
(c) quenching of free radicals and peroxides that contribute to tyrosinase activation and melanin formation; and d)
modulation of depigmenting abilities of melanocytotoxic agents. These concepts supported by the various experimental
evidence presented form basis for future research in the use of glutathione in the treatment of pigmentary disorders.

Abstract
International Journal of Cosmetic Science
Volume 27 Page 147 - June 2005
doi:10.1111/j.1467-2494.2005.00235.x

Glutathione as a depigmenting agent: an overview
C. D. Villarama*,† and H. I. Maibach*

Glutathione Research:

Health Benefits of Glutathione Supplementation

has anti-aging properties

helps the body fight almost any disease, because it is a powerful antioxidant that helps maintain cellular health and helps prevent oxidative stress

new studies suggest that it helps in alleviating the effects of neurodegenerative diseases like Alzheimer"s, Parkinson"s and Multiple Sclerosis

compelling evidence to suggest a crucial role for glutathione in the prevention and treatment of certain cancers

boosts the immune system

acts as an antioxidant and free radical scavenger protecting us against the damaging effects of pollutants and free radicals

reduces blood pressure in people with diabetes and with high blood pressure

increase sperm counts in men with low sperm counts

prevents clots formation in the blood

plays a vital role in liver detoxification and helps improve it"s function

recommended for people undergoing chemotherapy. According to studies, Glutathione reduces side effects of chemotherapy without reducing its efficacy

good for people who smoke and people who body builds since Glutathione is essential in muscle growth

What Doctors and Experts Say About Glutathione
Glutathione has been called the "master antioxidant", and regulates the actions of lesser antioxidants such as vitamin C, and vitamin E within the body. "We literally cannot survive without this antioxidant," Earl Mindell, R.Ph., Ph.D. "What You Should Know about the Super Antioxidant Miracle"

"No other antioxidant is as important to overall health as glutathione. It is the regulator and regenerator of immune cells and the most valuable detoxifying agent in the human body. Low levels are associated with hepatic dysfunction, immune dysfunction, cardiac disease, premature aging, and death." The Immune System Cure, Lorna R. Vanderhaeghe & Patrick J.D. Bouic, Ph.D.

Glutathione is the major endogenous antioxidant produced by the cell. Glutathione participates directly in the neutralization of free radicals, reactive oxygen compounds, and maintains exogenous antioxidants such as vitamins C and E in their reduced (active) forms. In addition, through direct conjugation, glutathione plays a role in the detoxification of many xenobiotics (foreign compounds) both organic and inorganic.

Research suggests that abnormally low glutathione levels may increase your risk for Heart Attack. Eric Topol, MD, New England Journal of Medicine.

"Glutathione has potent anti-viral properties - if tissue and serum glutathione levels are significantly increased, the replication of most pathogens are slowed or stopped. Conversely, glutathione deficiency produces a pro-viral effect." Paul Cheney, M.D., Ph.D. and expert in the treatment of Chronic Fatigue Syndrome.

As we age, there is a precipitous drop in Glutathione levels. Lower glutathione levels have been implicated in many diseases associated with aging. Journal of Clinical Epidemiology 47: 1021-28 1994

Antioxidants are well documented to play vital roles in health maintenance and disease prevention. Glutathione is your cells" own major antioxidant. Biochemical Pharmacology 47: 2113-2123 1994

Glutathione plays a role in eliminating many carcinogens as well as maintaining immune function. Cancer Letters 57: 91-94 1991

Strong muscular activity, such as that experienced by athletes, generates oxyradicals [free radicals] leading to muscle fatigue and poorer performance. Glutathione neutralizes these radicals. Sport Medicine 21: 213-238, 1996

Glutathione detoxifies many pollutants, carcinogens, and poisons, including many in fuel exhaust and cigarette smoke. It retards damage from radiation such as seen with loss of the ozone. Annual Reviews of Biochemistry 52: 711-780 1983

According to Lester Packer, Ph.D., maintaining high levels of glutathione is critical for life low glutathione levels are a marker for death at an early age. Glutathione diminishes as we age and cannot be boosted significantly through supplements.

Researchers have found that people over the age of 60 who have high blood levels of glutathione have fewer illnesses, lower cholesterol and blood pressure and healthier weights than people with lower levels. People over 69 with low blood levels of glutathione are more likely to have diabetes, arthritis and heart disease.

Glutathione and Skin Lightening:

We now know that Glutathione truly is an amazing anti-oxidant, immune booster and detoxifier but some people and even doctors aren"t aware and do not believe in it"s power to lighten the skin. It has been an open debate for years, people usually tackle the issue in forums, message boards and certain group discussions. From what we see, there are some people who do not believe and will disagree that Glutathione can lighten one"s complexion. However, there is concrete scientific fact that will suggest that it"s possible to lighten the skin by the means of Glutathione supplementation. Glutathione inhibits the function and activity of tyrosinase, which plays an important role in the biosynthesis of melanin. Technically speaking, Glutathione inhibits the Tyrosinase Activity which is the pathway of melanin, or in Layman"s term, the process where the skin achieves it"s color. When this pathway is intervened by the means of Glutathione, it then changes it"s pathway going to lighter pigmentation.

Imagine Tyrosinase Activity as a ship traveling the sea for a journey and Glutathione as the storm. Normally, when a ship travels, it has already planned it"s way to be able to reach it"s destination. However, when an unforeseen phenomena happens like for example a storm, it will most likely cancel its journey or make an alternative route to be able to reach it"s destination. This is what happens in the Tyrosinase Activity or the metabolic pathway of melanin. When there is the presence of Glutathione, the process of skin lightening will most likely to happen.

How Glutatione works
This is the inner layer of the skin called dermis and the outer surface which is visible in our eyes is the epidermis. The primary determinant of variability in human skin color is the melanin and melanocyte is a cell that synthesizes it. L-glutathione, the whitening pill"s main component, starts the lightening process in the dermis working its way out to the surface.

This is the point where the metabolic pathway of melanin begins. As you see in the diagram GSH(reduced glutathione) intervenes the metabolism. There are certain kinds of compounds that inhibits the tyrosinase activity and L-glutathione is one of them.

This is the point where the metabolic pathway of melanin begins. As you see in the diagram GSH(reduced glutathione) intervenes the metabolism. There are certain kinds of compounds that inhibits the tyrosinase activity and L-glutathione is one of them.

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Medicine is a constantly changing science and not all therapies are clearly established. New research changes drug and treatment therapies daily. The authors, editors, and publisher of this journal have used their best efforts to provide information that is up-to-date and accurate and is generally accepted within medical standards at the time of publication. However, as medical science is constantly changing andhuman error is always possible, the authors, editors, and publisher or any other party involved with the publication of this article do not warrant the information in this article is accurate or complete, nor are they responsible for omissions or errors in the article or for the results of using this information. The reader should confirm the information in this article from other sources prior to use. In particular, all drug doses, indications, and contraindications should be confirmed in the package insert.